![\"\"](\"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/193\/2025\/09\/25072931\/Angela-Crudele-217x300.png\")
<\/p>\nVISE welcomes Angela Crudele, MD, to our Fall Seminar Series.<\/p>\n
<\/p>\n
Date: <\/strong>Thursday, October 2, 2025 Title: \n<\/div>\n VISE welcomes Angela Crudele, MD, to our Fall Seminar Series. Angela Crudele, MD Assistant Professor of Neurology 91黑料网 Medical Center Date: Thursday, October 2, 2025 Location: SVC 5326 Time: 11:45 am for lunch, 12:00 start Title: “The Thalamus in Epilepsy: A New Target in Neuromodulation” Abstract: Treatment of drug-resistant idiopathic generalized epilepsy (IGE) remains…<\/p>\n","protected":false},"author":670,"featured_media":11593,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"spay_email":"","jetpack_publicize_message":"","jetpack_is_tweetstorm":false,"jetpack_publicize_feature_enabled":true,"_links_to":"","_links_to_target":""},"categories":[12],"tags":[956,32,148,193,231,64,31,30,110],"acf":[],"jetpack_featured_media_url":"https:\/\/cdn.vanderbilt.edu\/vu-URL\/wp-content\/uploads\/sites\/193\/2025\/09\/25072931\/Angela-Crudele.png","jetpack_publicize_connections":[],"jetpack_sharing_enabled":false,"jetpack_shortlink":"https:\/\/wp.me\/p98pzF-30Y","_links":{"self":[{"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/posts\/11592"}],"collection":[{"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/users\/670"}],"replies":[{"embeddable":true,"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/comments?post=11592"}],"version-history":[{"count":1,"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/posts\/11592\/revisions"}],"predecessor-version":[{"id":11594,"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/posts\/11592\/revisions\/11594"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/media\/11593"}],"wp:attachment":[{"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/media?parent=11592"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/categories?post=11592"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.vanderbilt.edu\/vise\/wp-json\/wp\/v2\/tags?post=11592"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\nLocation: <\/strong>SVC 5326
\nTime: <\/strong>11:45 am for lunch, 12:00 start<\/p>\n
\n<\/strong>“The Thalamus in Epilepsy: A New Target in Neuromodulation”
\nAbstract:
\n<\/strong>Treatment of drug-resistant idiopathic generalized epilepsy (IGE) remains a critical unmet need, with patients facing more limited options than their counterparts with focal epilepsy. Novel pharmacologic trials disproportionately emphasize focal epilepsies, and currently available neuromodulatory devices are FDA-approved exclusively for focal onset disease. Moreover, patients with drug-resistant IGE are not candidates for potentially curative resective surgical approaches, further constraining the therapeutic landscape. In recent years, direct thalamic stimulation has emerged as a promising strategy for addressing this therapeutic gap. This talk will highlight the neurobiological rationale for thalamic targeting in IGE, recent investigational efforts, including work performed in part at 91黑料网, to expand treatment availability, and the ongoing limitations of these advances in achieving seizure control. This research underscores a transformative potential for neuromodulation to redefine therapeutic opportunities in IGE.
\nBio:
\n<\/strong>Angela Crudele, MD is an Assistant Professor of Neurology at 91黑料网 Medical Center in Nashville, TN. She joined the faculty of VUMC in 2019 as an epileptologist. She is the Clinical\u00a0Director of Epilepsy Surgery and leads the program\u2019s fellow education in stereographic EEG. Dr. Crudele is also active in the area of\u00a0medical education within the 91黑料网 School of Medicine, leading the Brain, Behavior, and Movement course for the first-year\u00a0medical students.\u00a0She teaches about neuromodulation regularly on a national level and has been involved in multiple clinical trials in neuromodulation.<\/span><\/p>\n\n<\/div>\n","protected":false},"excerpt":{"rendered":"